A new review finds that obesity and aging affect many of the same biological systems, but shared pathways do not mean obesity literally makes someone older or that weight loss can turn back the clock.
A four-week trial found shifts in DNA methylation and immune patterns, but it did not show that participants aged more slowly.
A review of more than 350 studies found biological reasons lower-protein diets could support longevity, but most lifespan evidence comes from animals and reducing protein may be harmful for some older adults.
A phase 2 trial found improvement in liver fibrosis among some patients with MASH, though the main drug combination did not outperform its comparator.
A broad review found promising biological clues, but it did not establish that any food, compound or diet prevents Alzheimer’s disease.
A long-term study suggests lower-inflammatory eating patterns may be linked to lower dementia risk, even among older adults with biological signs of elevated risk.
A small pilot study found that a combined movement and protein program was feasible and well tolerated among frail older adults in skilled nursing facilities.
A long-term follow-up of the Diabetes Prevention Program links intensive lifestyle changes to a lower burden of multiple chronic conditions in older age.
A new modeling study found no overall health benefit from drinking, even at low levels, and estimated that the risk of alcohol-related harm increases as consumption rises.
A new observational study found that health differences remained even after researchers accounted for overall diet quality, but it cannot prove that processing caused them.
A two-year randomized clinical trial found older adults at risk for cognitive decline improved more on a frailty measure when lifestyle changes included coaching, goal setting and accountability.
A large BMJ review found routine supplements offered little to no meaningful benefit for most older adults, but the findings do not mean calcium and vitamin D are unimportant.
A small randomized trial in older adults found that four weeks of dietary changes improved some biomarkers tied to biological age, but that does not mean aging itself was reversed.
A major review of long-term studies found people who ate more legumes and soy foods were less likely to develop high blood pressure, though the research cannot prove these foods alone were responsible.
A large observational study of older adults found that people who ate eggs more often were less likely to be diagnosed with Alzheimer’s disease over time, though researchers cannot say eggs themselves were the cause.
Timing may matter as much as total weight, with earlier gains tied to longer exposure and greater risk.
Not all plant-based diets are created equal, with whole foods linked to lower risk and refined options tied to higher risk.
A new study finds that different metabolic patterns may predict who develops diabetes and related complications, even before diagnosis
A new study finds that modest improvements in sleep, diet, and activity together are linked to a lower risk of heart attack and stroke
Long-term data suggest a Mediterranean-style eating pattern may be tied to slower loss of brain volume, though researchers caution it’s not cause and effect
Researchers say aeroponic farming techniques could help deliver vitamin B12 through plant foods, potentially offering a new option for people who eat little or no animal products.
A randomized clinical trial found high-dose vitamin D supplements did not reduce COVID hospitalizations or symptom severity, though researchers observed a small signal suggesting fewer long COVID symptoms among participants who took the vitamin.
A large study of more than 160,000 adults found that people who ate more ultraprocessed foods tended to have lower bone mineral density and a modestly higher risk of hip fractures.
Researchers found that changes in the gut microbiome linked to a high-fat diet allowed small numbers of bacteria to travel to the brain in mice, pointing to a possible new pathway connecting diet and neurological health.
A study in hyperglycemic mice suggests a ketogenic diet restored aerobic adaptation to exercise, raising questions about how blood sugar may blunt training benefits.
